Adrenergic Receptors and Nephrone

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[Adrenergic receptors and nephrone].

It is well known that the renal nerve plays an important role in the regulation of renal functions such as sodium and water reabsorption in the tubules as well as in the pathogenesis of essential hypertension. The renal sympathetic nerves innervate to the basement membranes of almost all nephron segments. Specific adrenergic receptors and intracellular signal transduction systems are located in...

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Adrenergic Receptors

Neurons in the paraventricular nucleus (PVN) that project to the brainstem and spinal cord are important for autonomic regulation. The excitability of pre-autonomic PVN neurons is controlled by the noradrenergic input from the brainstem. In this study, we determined the role of " 2 adrenergic receptors in the regulation of excitatory and inhibitory synaptic inputs to spinally projecting PVN neu...

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Protein and a1-Adrenergic Receptors

The pathogenesis of the myopathy occurring in the heart of the cardiomyopathic strain of the Syrian hamster is not well understood but is believed to be associated with abnormal calcium handling by myopathic cells. The purpose of this study was to determine whether the cardiomyopathy occurring in strain BIO 14.6 animals is associated with an enhanced a1-adrenergic receptor-mediated rise in cyto...

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«2"Adrenergic Receptors

Although quinidine is known to have antiadrenergic effects in the cardiovascular system, the precise mechanism by which it exerts these effects is not well defined. We asked whether quinidine binds directly to adrenergic receptors. Radioligand-binding assays were used to identify <*i -adrenergic receptors ([H]prazosin-binding sites) on membranes prepared from rat heart and kidney, a2-adrenergic...

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Beta-Adrenergic Receptors

ion fluxes in these cells, we have now examined the possibility that the decrease in beta receptor number might be associated with concomitant changes in catecholamine-dependent potassium ion transport. Hypothyroid turkey erythrocytes display decreased sensitivity to isoproterenol-stimulated potassium influx. Half-maximal stimulation of potassium influx occurs at 9.2±+1.7 nM in hypothyroid cell...

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ژورنال

عنوان ژورنال: Folia Endocrinologica Japonica

سال: 1994

ISSN: 0029-0661

DOI: 10.1507/endocrine1927.70.9_979